Articles: Herxheimer reactions (herxing) with bartonella

“Some immunocompromised patients develop a potentially life-threatening Jarisch-Herxheimer-like reaction within hours after institution of antibiotic therapy. Physicians should advise patients of this possible treatment complication, and patients with severe respiratory and/or cardiovascular compromise should be monitored carefully following institution of antimicrobial therapy.”

Source: Recommendations for Treatment of Human Infections Caused by Bartonella Species.

“In addition, a systemic, toxic response resembling a Jarisch-Herxheimer reaction was observed in Patients 3 and 4 after they received the first several doses of an appropriate antibiotic. Both of these patients had a negative syphilis test. Kemper et al. described a similar toxic reaction after the first two doses of doxycycline in a patient with bacillary peliosis hepatis that was attributed to an adverse drug reaction. In addition to syphilis, the Jarisch-Herxheimer reaction has been described for leptospirosis, borreliosis, and brucellosis. Thus, immunodeficient patients may require indefinite antibiotic therapy and pretreatment with antipyretic agents to attenuate any Jarisch-Herxheimer reaction.

Source: Isolation of [Bartonella] species from cutaneous and osseous lesions of bacillary angiomatosis.


One thought on “Articles: Herxheimer reactions (herxing) with bartonella

  1. I had immediate severe reaction on rifmapin, lymes/bartonella, seems that epole s[pend life of herxing, I was in better shape before, to dangerous, took myself off four doses. bp went up, screaming, neurpoathy horrible, leg weakness..never doing it again..also my new dr for this does retun patient calls have to drive in, so i am done with her


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